GTF2E1

Across TCGA patient cohorts, GTF2E1 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,053 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GTF2E1-associated proteins across cancer lineages are UMPS, FXR1, and OSBPL11. Each is linked with GTF2E1 in more than 6 cancer types. Because this analysis shows association rather than direction, both GTF2E1-to-partner and partner-to-GTF2E1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GTF2E1 versus UMPS in LSCC, with a Pearson correlation of 0.72.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GTF2E1→partner) and Y-score (partner→GTF2E1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	UMPS →	+0.468	+0.750	<.001	<.001	3	7
LSCC	FXR1 →	+0.336	+0.544	<.001	<.001	3	6
LSCC	OSBPL11 →	+0.211	+0.564	.001	<.001	3	6
LUAD	MCM2_S27 →	+1.069	+0.568	<.001	<.001	3	5
LUAD	NCAPG_S674 →	+0.987	+0.428	<.001	<.001	3	5
BRCA	PAK2 →	+0.216	+0.489	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,053 associations by consensus.

GTF2E1 vs UMPS — LSCC

Explore this scatter interactively →