GTF2B

Across TCGA patient cohorts, GTF2B RNA expression is significantly associated with the protein abundance of many other proteins, with 7,922 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible GTF2B-associated proteins across cancer lineages are PKN2, AFAP1L2, and SND1. Each is linked with GTF2B in more than 4 cancer types. Because this analysis shows association rather than direction, both GTF2B-to-partner and partner-to-GTF2B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GTF2B versus PKN2 in LUAD, with a Pearson correlation of 0.49.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GTF2B→partner) and Y-score (partner→GTF2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	PKN2 →	+0.249	+0.307	<.001	<.001	3	5
COAD	AFAP1L2 →	+0.372	+0.427	<.001	<.001	3	4
HNSC	SND1 →	-0.203	-0.586	<.001	<.001	3	3
GBM	DNAJC3 →	-0.292	-0.221	.006	.003	3	3
HNSC	HSPA13 →	-0.303	-0.606	.004	.006	3	3
BRCA	MIER1 →	+0.214	+0.374	.004	.004	2	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,922 associations by consensus.

GTF2B vs PKN2 — LUAD

Explore this scatter interactively →