GTF2B

Across TCGA cell cohorts, GTF2B RNA expression is significantly associated with the go_rna of many other GO terms, with 3,161 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GTF2B-associated GO terms across cancer lineages are Zinc ion import into Golgi lumen, Regulation of lymphotoxin A production, and Positive regulation of lymphotoxin A production. Each is linked with GTF2B in more than 11 cancer types. Because this analysis shows association rather than direction, both GTF2B-to-partner and partner-to-GTF2B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Zinc ion import into Golgi lumen grouped by GTF2B-low versus GTF2B-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GTF2B→partner) and Y-score (partner→GTF2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Zinc ion import into Golgi lumen →	+0.107	+0.848	<.001	<.001	3	12
LUNG_NSCLC_LUSC	Regulation of lymphotoxin A production →	+0.946	+0.938	.007	<.001	3	11
LUNG_NSCLC_LUSC	Positive regulation of lymphotoxin A production →	+0.946	+0.938	.007	<.001	3	11
KIDNEY	Cytosol to Golgi apparatus transport →	+0.112	+0.448	.001	.002	3	10
SOFT_TISSUE	Response to staurosporine →	+0.152	+0.584	<.001	.002	3	9
SOFT_TISSUE	Cellular response to staurosporine →	+0.152	+0.584	<.001	.002	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,161 associations by consensus.

Zinc ion import into Golgi lumen by GTF2B expression — PANCREAS

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