GSX1

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, GSX1 RNA expression is significantly associated with the protein abundance of many other proteins, with 5,872 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GSX1-associated proteins across cancer lineages are ZNF335_S992, CD44, and GTF2F2. Each is linked with GSX1 in more than 1 cancer types. Because this analysis shows association rather than direction, both GSX1-to-partner and partner-to-GSX1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GSX1 versus ZNF335_S992 in HNSC, with a Pearson correlation of 0.27.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GSX1→partner) and Y-score (partner→GSX1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
HNSCZNF335_S992 →+0.521+0.254.001.00532
GBMCD44 →-0.494-0.940.003.00532
GBMGTF2F2 →+0.349+0.915<.001<.00132
GBMHMGB1 →+0.308+1.047<.001<.00132
GBMHMOX1 →-0.417-0.604.001.00532
LSCCACIN1_S729 →+0.289+0.012.007.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 5,872 associations by consensus.

GSX1 vs ZNF335_S992 — HNSC

Per-sample scatter of GSX1 vs ZNF335_S992 in HNSC (Pearson r = 0.27).

Explore this scatter interactively →

Exploration