GSTT4

Across TCGA patient cohorts, GSTT4 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,461 significant associations in total. STAD shows the largest number of these associations.

The most reproducible GSTT4-associated GO terms across cancer lineages are Regulation of microtubule-based process, Nucleoside phosphate biosynthetic process, and Double-strand break repair via nonhomologous end joining. Each is linked with GSTT4 in more than 14 cancer types. Because this analysis shows association rather than direction, both GSTT4-to-partner and partner-to-GSTT4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of microtubule-based process grouped by GSTT4-low versus GSTT4-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GSTT4→partner) and Y-score (partner→GSTT4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Regulation of microtubule-based process →	+0.041	+0.255	<.001	<.001	3	15
STAD	Nucleoside phosphate biosynthetic process →	+0.052	+0.217	<.001	<.001	3	14
STAD	Double-strand break repair via nonhomologous end joining →	+0.050	+0.225	<.001	<.001	3	14
STAD	Positive regulation of DNA metabolic process →	+0.055	+0.256	<.001	<.001	3	14
STAD	Regulation of microtubule cytoskeleton organization →	+0.049	+0.246	<.001	<.001	3	14
STAD	Positive regulation of post-translational protein modification →	+0.057	+0.219	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,461 associations by consensus.

Regulation of microtubule-based process by GSTT4 expression — STAD

Explore this box plot interactively →