GSTT4

Across TCGA cell cohorts, GSTT4 RNA expression is significantly associated with the mutation status of many other genes, with 228 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GSTT4-associated genes across cancer lineages are ITSN2, ANKRD26, and EXPH5. Each is linked with GSTT4 in more than 1 cancer types. Because this analysis shows association rather than direction, both GSTT4-to-partner and partner-to-GSTT4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ITSN2 grouped by GSTT4-low versus GSTT4-high in BLOOD_Myeloma.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GSTT4→partner) and Y-score (partner→GSTT4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	ITSN2 →	+3.716	+0.022	.005	.006	3	2
LUNG_NSCLC_LUSC	ANKRD26 →	+4.643	+0.013	.008	<.001	3	2
LUNG_NSCLC_LUSC	EXPH5 →	+4.643	+0.013	.008	<.001	3	2
LUNG_NSCLC_LUSC	CHD5 →	+4.643	+0.013	.008	<.001	3	2
BLOOD_Lymphoma	IGSF9B →	+3.669	+0.046	.003	<.001	3	2
LUNG_NSCLC_LUSC	RHOT1 →	+4.643	+0.013	.008	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 228 associations by consensus.

ITSN2 by GSTT4 expression — BLOOD_Myeloma

Explore this box plot interactively →