GSTO2

Across TCGA patient cohorts, GSTO2 mutation is significantly associated with the RNA expression of many other genes, with 130 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GSTO2-associated genes across cancer lineages are RN7SL456P, ANKRD20A6P, and RN7SL470P. Each is linked with GSTO2 in more than 1 cancer types. Because this analysis shows association rather than direction, both GSTO2-to-partner and partner-to-GSTO2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL456P grouped by GSTO2-low versus GSTO2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GSTO2→partner) and Y-score (partner→GSTO2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RN7SL456P →	+0.280	+3.021	<.001	.002	3	2
BRCA	ANKRD20A6P →	+0.194	+8.055	<.001	.007	3	1
UCEC	RN7SL470P →	+0.298	+2.694	<.001	.005	3	1
UCEC	DUXAP3 →	+0.225	+2.940	<.001	.002	3	1
SKCM	RNU4-60P →	+0.383	+5.224	<.001	.007	3	1
STAD	MIR4289 →	+0.427	+4.798	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 130 associations by consensus.

RN7SL456P by GSTO2 expression — UCEC

Explore this box plot interactively →