GSTM4

Across TCGA patient cohorts, GSTM4 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,614 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GSTM4-associated proteins across cancer lineages are GSTM3, TMSB10, and RPS6. Each is linked with GSTM4 in more than 5 cancer types. Because this analysis shows association rather than direction, both GSTM4-to-partner and partner-to-GSTM4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GSTM4 versus GSTM3 in LSCC, with a Pearson correlation of 0.73.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GSTM4→partner) and Y-score (partner→GSTM4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	GSTM3 →	+1.385	+0.927	<.001	<.001	3	6
BRCA	TMSB10 →	-0.484	-0.729	.002	.001	3	5
GBM	RPS6 →	-0.400	-0.306	.001	.005	3	5
BRCA	DDAH1 →	+0.868	+1.130	<.001	<.001	3	5
GBM	MAP3K4_S431 →	-0.422	-0.368	<.001	<.001	3	4
BRCA	NARF →	-0.669	-0.974	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,614 associations by consensus.

GSTM4 vs GSTM3 — LSCC

Explore this scatter interactively →