Across TCGA patient cohorts, GSTM2 RNA expression is significantly associated with the protein abundance of many other proteins, with 19,308 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GSTM2-associated proteins across cancer lineages are KANK2, AGO1, and LRP1. Each is linked with GSTM2 in more than 6 cancer types. Because this analysis shows association rather than direction, both GSTM2-to-partner and partner-to-GSTM2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GSTM2→partner) and Y-score (partner→GSTM2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	KANK2 →	+0.488	+0.976	<.001	<.001	3	7
UCEC	AGO1 →	+0.265	+0.599	.001	<.001	3	7
UCEC	LRP1 →	+0.584	+0.824	<.001	<.001	3	6
LSCC	GSTM4 →	+1.716	+1.079	<.001	<.001	3	6
BRCA	NAXE →	+0.357	+1.064	<.001	<.001	3	6
LSCC	PLCD1 →	+0.605	+1.348	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,308 associations by consensus.

Exploration

GSTM2 survival (RNA) · tumor vs normal (RNA) · all GSTM2 data types