Across TCGA patient cohorts, GSTK1 mutation is significantly associated with the RNA expression of many other genes, with 870 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GSTK1-associated genes across cancer lineages are OR1D4, MIR502, and VDAC2P4. Each is linked with GSTK1 in more than 1 cancer types. Because this analysis shows association rather than direction, both GSTK1-to-partner and partner-to-GSTK1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GSTK1→partner) and Y-score (partner→GSTK1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	OR1D4 →	+0.039	+5.800	.003	.003	3	2
BLCA	MIR502 →	+0.488	+7.640	<.001	.009	3	2
CESC	VDAC2P4 →	+0.127	+5.010	<.001	.009	3	2
CESC	VN1R93P →	+0.066	+5.418	.001	.005	3	2
CESC	MIR8070 →	+0.670	+5.103	<.001	.008	3	2
UCEC	RNA5SP411 →	+0.871	+1.808	.001	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 870 associations by consensus.

Exploration

GSTK1 survival (RNA) · tumor vs normal (RNA) · all GSTK1 data types