GSTA7P

Across TCGA pan-cancer cohorts, GSTA7P RNA differs between tumor and matched normal tissue in 8 of 18 cancer types tested, making tumor–normal expression one of GSTA7P’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where GSTA7P RNA is repressed in tumor relative to normal tissue. In most cancer types GSTA7P is over-expressed in tumor, although a few such as KIRP and KICH show the opposite, repressed pattern.

KIRP, KIRC, and KICH are the cancer types where GSTA7P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in GSTA7P RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRP	Male	All	−1.779	<.001	9	view →
KIRC	All	II,III,IV	+0.927	<.001	8	view →
KICH	All	II,III,IV	−1.734	<.001	7	view →
CHOL	All	All	−2.050	<.001	5	view →
LUAD	All	II,III,IV	−0.136	.006	4	view →
HNSC	Male	III,IV	+0.278	.035	2	view →
LIHC	Female	All	−0.921	.026	1	view →
STAD	Male	II,III,IV	−0.131	.045	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 8 strongest of 8 lineages.

GSTA7P–KIRP

Open the KIRP breakdown →