GSTA5

Across TCGA pan-cancer cohorts, GSTA5 Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated GSTA5 data layer compared with 11 for mass-spec protein.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher GSTA5 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated GSTA5 expression acts as an unfavorable survival marker.

BLCA, COAD, and LUSC are the cancer types where GSTA5 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BLCA	OS	Median	All	0.162	0.610	<.001	48	view →
COAD	OS	Median	All	0.125	0.801	<.001	33	view →
LUSC	OS	Median	All	0.182	0.676	.004	24	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

GSTA5–BLCA (OS)

Open the BLCA breakdown →