GSTA4

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, GSTA4 protein abundance is significantly associated with the RNA expression of many other genes, with 17,881 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GSTA4-associated genes across cancer lineages are ADAM8, GSTA3, and CILK1. Each is linked with GSTA4 in more than 5 cancer types. Because this analysis shows association rather than direction, both GSTA4-to-partner and partner-to-GSTA4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GSTA4 versus ADAM8 in GBM, with a Pearson correlation of -0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GSTA4→partner) and Y-score (partner→GSTA4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMADAM8 →-0.824-0.479<.001<.00136
BRCAGSTA3 →+1.019+0.606.006<.00136
LSCCCILK1 →+1.113+1.361<.001<.00135
BRCAGARNL3 →+0.827+0.513<.001.00135
GBMGAPDHP15 →+1.301+0.712<.001<.00135
HNSCCD86 →-0.874-1.012<.001<.00135
Each partner links to its Q-omics profile. Showing the 6 strongest of 17,881 associations by consensus.

GSTA4 vs ADAM8 — GBM

Per-sample scatter of GSTA4 vs ADAM8 in GBM (Pearson r = -0.35).

Explore this scatter interactively →

Exploration