GSTA4

Across TCGA pan-cancer cohorts, GSTA4 RNA differs between tumor and matched normal tissue in 10 of 18 cancer types tested, making tumor–normal expression one of GSTA4’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where GSTA4 RNA is repressed in tumor relative to normal tissue. In most cancer types GSTA4 is over-expressed in tumor, although a few such as KICH and LUAD show the opposite, repressed pattern.

KICH, LUAD, and LIHC are the cancer types where GSTA4 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in GSTA4 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	All	IV	−2.822	<.001	11	view →
LUAD	Male	III,IV	−1.881	<.001	11	view →
LIHC	Male	All	+1.469	<.001	8	view →
THCA	All	All	−0.399	<.001	7	view →
KIRP	All	All	−0.655	<.001	6	view →
BRCA	Female	All	−0.474	<.001	6	view →
STAD	All	All	−0.727	.009	4	view →
HNSC	All	All	−0.657	.007	3	view →
BLCA	All	IV	−1.191	.026	1	view →
KIRC	Female	All	+0.374	.026	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 10 strongest of 10 lineages.

GSTA4–KICH

Open the KICH breakdown →