GSTA4

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, GSTA4 mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible GSTA4-associated genes across cancer lineages are SIRPD. Each is linked with GSTA4 in more than 1 cancer types. Because this analysis shows association rather than direction, both GSTA4-to-partner and partner-to-GSTA4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SIRPD grouped by GSTA4-low versus GSTA4-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GSTA4→partner) and Y-score (partner→GSTA4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINESIRPD →+0.021+4.977<.001.00731
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

SIRPD by GSTA4 expression — LARGE_INTESTINE

Box plot of SIRPD in GSTA4-low vs GSTA4-high samples in LARGE_INTESTINE.

Explore this box plot interactively →

Exploration