GSTA2

Across TCGA patient cohorts, GSTA2 mutation is significantly associated with the total protein of many other genes, with 13 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GSTA2-associated genes across cancer lineages are p62 Lck ligand, PCNA, and Annexin-1. Each is linked with GSTA2 in more than 1 cancer types. Because this analysis shows association rather than direction, both GSTA2-to-partner and partner-to-GSTA2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, p62 Lck ligand grouped by GSTA2-low versus GSTA2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GSTA2→partner) and Y-score (partner→GSTA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	p62 Lck ligand →	+0.453	+2.321	.005	.035	3	1
UCEC	PCNA →	+0.305	+3.169	.004	.019	3	1
UCEC	Annexin-1 →	+0.607	+3.019	.021	.019	3	1
UCEC	Caspase-7-cleavedD198 →	+0.792	+3.019	.007	.019	3	1
UCEC	4E-BP1_pT70 →	+0.124	+2.321	.031	.035	3	1
UCEC	AR →	-0.422	-2.321	.024	.035	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 13 associations by consensus.

p62 Lck ligand by GSTA2 expression — UCEC

Explore this box plot interactively →