GSTA2

Across TCGA pan-cancer cohorts, GSTA2 RNA differs between tumor and matched normal tissue in 9 of 18 cancer types tested, making tumor–normal expression one of GSTA2’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where GSTA2 RNA is repressed in tumor relative to normal tissue. In most cancer types GSTA2 is over-expressed in tumor, although a few such as KIRP and KICH show the opposite, repressed pattern.

KIRP, KICH, and LUSC are the cancer types where GSTA2 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in GSTA2 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRP	Male	All	−5.551	<.001	11	view →
KICH	Male	II,III,IV	−6.230	<.001	8	view →
LUSC	Male	II,III,IV	−2.489	<.001	8	view →
KIRC	All	II,III,IV	+1.626	.004	6	view →
LUAD	All	II,III,IV	−1.320	<.001	6	view →
CHOL	All	All	−6.716	<.001	5	view →
LIHC	All	All	−1.880	<.001	4	view →
PRAD	All	All	−0.848	<.001	2	view →
READ	All	All	−0.236	.010	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 9 strongest of 9 lineages.

GSTA2–KIRP

Open the KIRP breakdown →