Across TCGA cell cohorts, GSPT2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,656 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GSPT2-associated GO terms across cancer lineages are Transcription initiation at RNA polymerase II promoter, Protein-DNA complex organization, and Regulation of cytoplasmic translational initiation. Each is linked with GSPT2 in more than 6 cancer types. Because this analysis shows association rather than direction, both GSPT2-to-partner and partner-to-GSPT2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GSPT2→partner) and Y-score (partner→GSPT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Transcription initiation at RNA polymerase II promoter →	+0.072	+2.422	<.001	<.001	3	7
BONE	Protein-DNA complex organization →	+0.076	+1.016	<.001	.002	3	7
SKIN	Regulation of cytoplasmic translational initiation →	+0.113	+1.301	<.001	<.001	3	7
BLOOD_Leukemia	Hormone transport →	-0.078	-1.368	<.001	<.001	3	6
SKIN	Cytoskeleton-dependent intracellular transport →	+0.035	+1.240	.001	.002	3	6
UPPER_AERODIGESTIVE_TRACT	Positive regulation of telomere maintenance via telomerase →	+0.072	+1.105	.006	.002	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,656 associations by consensus.

Exploration

GSPT2 survival (RNA) · tumor vs normal (RNA) · all GSPT2 data types