GSN

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, GSN RNA expression is significantly associated with the protein abundance of many other proteins, with 22,967 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GSN-associated proteins across cancer lineages are DDX18, MYO1C, and TOP1. Each is linked with GSN in more than 6 cancer types. Because this analysis shows association rather than direction, both GSN-to-partner and partner-to-GSN results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GSN versus DDX18 in COAD, with a Pearson correlation of -0.40.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GSN→partner) and Y-score (partner→GSN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
COADDDX18 →-0.312-0.696<.001<.00137
GBMMYO1C →+0.440+0.893<.001<.00137
COADTOP1 →-0.468-0.717<.001<.00137
PDACCAPN2 →+0.434+0.421<.001.00136
BRCACAVIN1 →+0.701+0.776<.001<.00136
BRCACAVIN3 →+0.671+0.803<.001<.00136
Each partner links to its Q-omics profile. Showing the 6 strongest of 22,967 associations by consensus.

GSN vs DDX18 — COAD

Per-sample scatter of GSN vs DDX18 in COAD (Pearson r = -0.40).

Explore this scatter interactively →

Exploration