GSDMA

Across TCGA patient cohorts, GSDMA protein abundance is significantly associated with the RNA expression of many other genes, with 11,625 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible GSDMA-associated genes across cancer lineages are DCUN1D3, NCBP2, and AGAP2. Each is linked with GSDMA in more than 3 cancer types. Because this analysis shows association rather than direction, both GSDMA-to-partner and partner-to-GSDMA results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GSDMA versus DCUN1D3 in UCEC, with a Pearson correlation of 0.51.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GSDMA→partner) and Y-score (partner→GSDMA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	DCUN1D3 →	+0.471	+1.045	<.001	.001	3	4
HNSC	NCBP2 →	-0.946	-1.626	<.001	<.001	3	4
BRCA	AGAP2 →	+0.533	+0.592	<.001	.001	3	3
CCRCC	KCNA3 →	+1.295	+0.781	.002	<.001	3	3
CCRCC	CCNB1IP1 →	-0.836	-0.635	<.001	.004	3	3
HNSC	RBFA →	-0.356	-0.927	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,625 associations by consensus.

GSDMA vs DCUN1D3 — UCEC

Explore this scatter interactively →