GSC2

Across TCGA patient cohorts, GSC2 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,875 significant associations in total. STAD shows the largest number of these associations.

The most reproducible GSC2-associated GO terms across cancer lineages are Protein localization to chromosome, Regulation of microtubule cytoskeleton organization, and mRNA 3'-end processing. Each is linked with GSC2 in more than 14 cancer types. Because this analysis shows association rather than direction, both GSC2-to-partner and partner-to-GSC2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein localization to chromosome grouped by GSC2-low versus GSC2-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GSC2→partner) and Y-score (partner→GSC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Protein localization to chromosome →	+0.059	+0.069	<.001	<.001	3	15
ESCA	Regulation of microtubule cytoskeleton organization →	+0.056	+0.224	<.001	.004	3	15
STAD	mRNA 3'-end processing →	+0.058	+0.060	<.001	<.001	3	14
SCLC	Regulation of microtubule-based process →	+0.055	+0.140	<.001	.004	3	14
STAD	Ribosomal large subunit biogenesis →	+0.068	+0.061	<.001	<.001	3	14
STAD	Transcription initiation at RNA polymerase II promoter →	+0.059	+0.062	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,875 associations by consensus.

Protein localization to chromosome by GSC2 expression — STAD

Explore this box plot interactively →