GSC2

Across TCGA patient cohorts, GSC2 protein abundance is significantly associated with the RNA expression of many other genes, with 458 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GSC2-associated genes across cancer lineages are SEC14L2, CENPM, and TCF20. Each is linked with GSC2 in more than 1 cancer types. Because this analysis shows association rather than direction, both GSC2-to-partner and partner-to-GSC2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GSC2 versus SEC14L2 in GBM, with a Pearson correlation of 0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GSC2→partner) and Y-score (partner→GSC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SEC14L2 →	+0.669	+0.845	.001	.001	3	1
GBM	CENPM →	-0.644	-0.583	.008	.005	3	1
GBM	TCF20 →	-0.451	-0.912	<.001	.001	3	1
GBM	JOSD1 →	-0.382	-0.782	<.001	.005	3	1
GBM	RHBDD3 →	-0.351	-0.851	.004	.001	3	1
GBM	CERK →	-0.462	-0.824	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 458 associations by consensus.

GSC2 vs SEC14L2 — GBM

Explore this scatter interactively →