GSC2

Across TCGA cell cohorts, GSC2 RNA expression is significantly associated with the go_rna of many other GO terms, with 446 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible GSC2-associated GO terms across cancer lineages are Double-strand break repair, Double-strand break repair via homologous recombination, and Recombinational repair. Each is linked with GSC2 in more than 5 cancer types. Because this analysis shows association rather than direction, both GSC2-to-partner and partner-to-GSC2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Double-strand break repair grouped by GSC2-low versus GSC2-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GSC2→partner) and Y-score (partner→GSC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Double-strand break repair →	+0.054	+0.029	.002	.006	3	6
SOFT_TISSUE	Double-strand break repair via homologous recombination →	+0.068	+0.029	<.001	.006	3	5
SOFT_TISSUE	Recombinational repair →	+0.070	+0.029	<.001	.006	3	5
LUNG_SCLC	Positive regulation of double-strand break repair →	+0.071	+0.101	<.001	.009	3	4
LUNG_NSCLC_LUAD	Nuclear DNA replication →	+0.057	+0.034	.002	.002	3	4
LUNG_NSCLC_LUAD	Cell cycle DNA replication →	+0.058	+0.025	.003	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 446 associations by consensus.

Double-strand break repair by GSC2 expression — SOFT_TISSUE

Explore this box plot interactively →