Across TCGA patient cohorts, GSAP mutation is significantly associated with the RNA expression of many other genes, with 2,023 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GSAP-associated genes across cancer lineages are PATL1, ZBTB17, and CYCSP44. Each is linked with GSAP in more than 2 cancer types. Because this analysis shows association rather than direction, both GSAP-to-partner and partner-to-GSAP results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GSAP→partner) and Y-score (partner→GSAP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	PATL1 →	+0.468	+2.604	.009	.006	3	3
UCEC	ZBTB17 →	+0.313	+2.550	.005	<.001	3	3
BRCA	CYCSP44 →	+0.134	+4.539	.006	.005	3	3
UCEC	CHAF1A →	+0.584	+2.223	<.001	<.001	3	3
UCEC	NUP188 →	+0.382	+1.874	.005	.002	3	3
SKCM	FXYD6P1 →	+0.085	+2.801	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,023 associations by consensus.

Exploration

GSAP survival (RNA) · tumor vs normal (RNA) · all GSAP data types