Across TCGA cell cohorts, GSAP mutation is significantly associated with the RNA expression of many other genes, with 25 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible GSAP-associated genes across cancer lineages are TRH, NPVF, and LEUTX. Each is linked with GSAP in more than 1 cancer types. Because this analysis shows association rather than direction, both GSAP-to-partner and partner-to-GSAP results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GSAP→partner) and Y-score (partner→GSAP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	TRH →	+0.046	+2.954	.003	.005	3	2
LUNG_NSCLC_LUAD	NPVF →	+0.014	+4.662	<.001	.005	3	2
SKIN	LEUTX →	+0.070	+5.217	<.001	<.001	3	2
LUNG_SCLC	OR10H5 →	+0.055	+4.044	.001	.009	3	1
STOMACH	KRTAP4-6 →	+0.075	+2.695	.003	.009	3	1
LARGE_INTESTINE	SH3GL2 →	+1.319	+3.474	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 25 associations by consensus.

Exploration

GSAP survival (RNA) · tumor vs normal (RNA) · all GSAP data types