GRWD1

Across TCGA patient cohorts, GRWD1 protein abundance is significantly associated with the RNA expression of many other genes, with 13,025 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GRWD1-associated genes across cancer lineages are C8orf33, VRK1, and LIG1. Each is linked with GRWD1 in more than 8 cancer types. Because this analysis shows association rather than direction, both GRWD1-to-partner and partner-to-GRWD1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GRWD1 versus C8orf33 in UCEC, with a Pearson correlation of 0.47.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GRWD1→partner) and Y-score (partner→GRWD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	C8orf33 →	+0.954	+0.292	<.001	<.001	3	9
UCEC	VRK1 →	+0.505	+0.191	<.001	<.001	3	6
UCEC	LIG1 →	+0.701	+0.225	<.001	<.001	3	6
LSCC	RUVBL2 →	+0.601	+0.330	<.001	<.001	3	6
UCEC	KNSTRN →	+0.604	+0.176	<.001	<.001	3	5
OV	ZNF473 →	+0.504	+0.252	.001	.003	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,025 associations by consensus.

GRWD1 vs C8orf33 — UCEC

Explore this scatter interactively →