GRWD1

Across TCGA patient cohorts, GRWD1 mutation is significantly associated with the RNA expression of many other genes, with 254 significant associations in total. BLCA shows the largest number of these associations.

The most reproducible GRWD1-associated genes across cancer lineages are OR7A17, OR10G3, and RNA5SP325. Each is linked with GRWD1 in more than 2 cancer types. Because this analysis shows association rather than direction, both GRWD1-to-partner and partner-to-GRWD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR7A17 grouped by GRWD1-low versus GRWD1-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GRWD1→partner) and Y-score (partner→GRWD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	OR7A17 →	+0.081	+5.038	<.001	.009	3	3
BLCA	OR10G3 →	+0.063	+5.788	<.001	.003	3	2
BLCA	RNA5SP325 →	+0.725	+6.018	<.001	.002	3	2
BLCA	RNU6-1151P →	+1.011	+7.307	<.001	<.001	3	2
LUSC	SNURFL →	+0.566	+5.625	<.001	.004	3	2
HNSC	SNORD114-24 →	+0.456	+7.357	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 254 associations by consensus.

OR7A17 by GRWD1 expression — BLCA

Explore this box plot interactively →