GRWD1

Across TCGA cell cohorts, GRWD1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,387 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible GRWD1-associated GO terms across cancer lineages are Transcription by RNA polymerase I, Transcription initiation at RNA polymerase I promoter, and rRNA transcription. Each is linked with GRWD1 in more than 18 cancer types. Because this analysis shows association rather than direction, both GRWD1-to-partner and partner-to-GRWD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Transcription by RNA polymerase I grouped by GRWD1-low versus GRWD1-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GRWD1→partner) and Y-score (partner→GRWD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Transcription by RNA polymerase I →	+0.134	+1.441	<.001	<.001	3	19
OESOPHAGUS	Transcription initiation at RNA polymerase I promoter →	+0.174	+1.333	<.001	.001	3	19
OESOPHAGUS	rRNA transcription →	+0.163	+1.397	<.001	.001	3	19
OESOPHAGUS	Maturation of 5.8S rRNA →	+0.141	+1.488	<.001	<.001	3	18
OESOPHAGUS	Maturation of SSU-rRNA →	+0.130	+1.134	<.001	<.001	3	18
OVARY	Nucleosome disassembly →	+0.182	+1.198	<.001	<.001	3	18

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,387 associations by consensus.

Transcription by RNA polymerase I by GRWD1 expression — LARGE_INTESTINE

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