GRPEL2

Across TCGA patient cohorts, GRPEL2 protein abundance is significantly associated with the RNA expression of many other genes, with 11,613 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GRPEL2-associated genes across cancer lineages are CCNB1, CDC25C, and GGTA1. Each is linked with GRPEL2 in more than 6 cancer types. Because this analysis shows association rather than direction, both GRPEL2-to-partner and partner-to-GRPEL2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GRPEL2 versus CCNB1 in LUAD, with a Pearson correlation of 0.52.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GRPEL2→partner) and Y-score (partner→GRPEL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	CCNB1 →	+1.534	+0.837	<.001	<.001	3	7
UCEC	CDC25C →	+1.160	+0.594	.001	<.001	3	6
GBM	GGTA1 →	-1.016	-0.636	<.001	<.001	3	6
LUAD	DEPDC1B →	+1.324	+0.747	<.001	<.001	3	6
UCEC	ARHGEF6 →	-1.011	-0.697	<.001	<.001	3	6
UCEC	FLI1 →	-0.612	-0.525	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,613 associations by consensus.

GRPEL2 vs CCNB1 — LUAD

Explore this scatter interactively →