GRPEL2

Across TCGA patient cohorts, GRPEL2 mutation is significantly associated with the RNA expression of many other genes, with 209 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GRPEL2-associated genes across cancer lineages are RN7SL808P, RNU6-364P, and MIR1283-2. Each is linked with GRPEL2 in more than 1 cancer types. Because this analysis shows association rather than direction, both GRPEL2-to-partner and partner-to-GRPEL2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL808P grouped by GRPEL2-low versus GRPEL2-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GRPEL2→partner) and Y-score (partner→GRPEL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RN7SL808P →	+0.116	+6.810	<.001	<.001	3	2
COAD	RNU6-364P →	+0.418	+7.741	<.001	.009	3	1
COAD	MIR1283-2 →	+0.488	+7.741	<.001	.009	3	1
COAD	RN7SKP223 →	+0.613	+7.741	<.001	.009	3	1
COAD	OR7E154P →	+0.044	+7.741	<.001	.009	3	1
UCEC	CXCL13 →	+2.202	+3.700	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 209 associations by consensus.

RN7SL808P by GRPEL2 expression — SKCM

Explore this box plot interactively →