GRPEL2

Across TCGA cell cohorts, GRPEL2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,184 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible GRPEL2-associated GO terms across cancer lineages are Positive regulation of mitochondrial RNA catabolic process, Regulation of centriole elongation, and tRNA modification. Each is linked with GRPEL2 in more than 12 cancer types. Because this analysis shows association rather than direction, both GRPEL2-to-partner and partner-to-GRPEL2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of mitochondrial RNA catabolic process grouped by GRPEL2-low versus GRPEL2-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GRPEL2→partner) and Y-score (partner→GRPEL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Positive regulation of mitochondrial RNA catabolic process →	+0.128	+0.818	.002	.002	3	13
UPPER_AERODIGESTIVE_TRACT	Regulation of centriole elongation →	+0.109	+0.940	<.001	.001	3	12
SOFT_TISSUE	tRNA modification →	+0.048	+0.898	<.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	Centriole replication →	+0.088	+0.807	<.001	<.001	3	11
BONE	Protein modification by small protein removal →	+0.033	+0.533	.003	.008	3	11
SOFT_TISSUE	Extracellular structure organization →	-0.141	-0.640	.002	.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,184 associations by consensus.

Positive regulation of mitochondrial RNA catabolic process by GRPEL2 expression — LIVER

Explore this box plot interactively →