GRP

Across TCGA patient cohorts, GRP RNA expression is significantly associated with the protein abundance of many other proteins, with 14,200 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible GRP-associated proteins across cancer lineages are CNN2, MAP1A, and CNN3. Each is linked with GRP in more than 7 cancer types. Because this analysis shows association rather than direction, both GRP-to-partner and partner-to-GRP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GRP versus CNN2 in BRCA, with a Pearson correlation of 0.57.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GRP→partner) and Y-score (partner→GRP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	CNN2 →	+0.578	+1.888	<.001	<.001	3	8
LSCC	MAP1A →	+0.753	+1.365	<.001	<.001	3	8
OV	CNN3 →	+0.786	+1.249	<.001	<.001	3	7
BRCA	COMP →	+1.356	+1.977	<.001	<.001	3	7
BRCA	DPYSL3 →	+0.732	+1.992	<.001	<.001	3	7
OV	FHL3 →	+0.672	+0.987	.001	.003	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,200 associations by consensus.

GRP vs CNN2 — BRCA

Explore this scatter interactively →