GRP

Across TCGA cell cohorts, GRP RNA expression is significantly associated with the RNA expression of many other genes, with 8,683 significant associations in total. BONE shows the largest number of these associations.

The most reproducible GRP-associated genes across cancer lineages are CALCA, CSNK2A3, and SETSIP. Each is linked with GRP in more than 7 cancer types. Because this analysis shows association rather than direction, both GRP-to-partner and partner-to-GRP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GRP versus CALCA in LUNG_SCLC, with a Pearson correlation of 0.59.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GRP→partner) and Y-score (partner→GRP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	CALCA →	+5.410	+5.818	<.001	<.001	3	8
UPPER_AERODIGESTIVE_TRACT	CSNK2A3 →	+1.136	+0.093	<.001	<.001	3	7
UPPER_AERODIGESTIVE_TRACT	SETSIP →	+0.804	+0.082	<.001	.001	2	8
UPPER_AERODIGESTIVE_TRACT	H3-5 →	+0.763	+0.082	.001	<.001	2	6
BREAST	KIF4B →	+0.140	+0.100	<.001	<.001	2	6
UPPER_AERODIGESTIVE_TRACT	PGAM4 →	+0.408	+0.110	<.001	<.001	2	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,683 associations by consensus.

GRP vs CALCA — LUNG_SCLC

Explore this scatter interactively →