GRM8-AS1

Across TCGA pan-cancer cohorts, GRM8-AS1 RNA is linked to patient survival in 6 of 34 cancer types, making it the most broadly survival-associated GRM8-AS1 data layer.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher GRM8-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated GRM8-AS1 expression acts as an unfavorable survival marker.

LUAD, UCEC, and BLCA are the cancer types where GRM8-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	DFS	Tertile	IV	0.272	0.752	.001	54	view →
UCEC	DFS	Tertile	III,IV	0.096	0.594	.008	48	view →
BLCA	OS	Tertile	IV	0.199	0.617	<.001	27	view →
SKCM	OS	Tertile	IV	0.226	0.613	.034	9	view →
ACC	DFS	Tertile	III,IV	0.048	0.362	.029	9	view →
PCPG	OS	Tertile	All	0.797	1.000	.010	3	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

GRM8-AS1–LUAD (DFS)

Open the LUAD breakdown →