GRM8-AS1

Across TCGA pan-cancer cohorts, GRM8-AS1 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of GRM8-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where GRM8-AS1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types GRM8-AS1 is over-expressed in tumor, although a few such as THCA show the opposite, repressed pattern.

COAD, THCA, and STAD are the cancer types where GRM8-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in GRM8-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	All	II,III,IV	+0.019	.041	3	view →
THCA	All	All	−0.003	.022	2	view →
STAD	All	All	+0.011	.038	1	view →
LUSC	All	All	+0.003	.047	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

GRM8-AS1–COAD

Open the COAD breakdown →