GRM7-AS2

Across TCGA pan-cancer cohorts, GRM7-AS2 RNA is linked to patient survival in 13 of 34 cancer types, making it the most broadly survival-associated GRM7-AS2 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher GRM7-AS2 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated GRM7-AS2 expression acts as an unfavorable survival marker, although some lineages such as PAAD and LUAD show a favorable association.

KIRC, LIHC, and THCA are the cancer types where GRM7-AS2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Tertile	IV	0.198	0.634	<.001	96	view →
LIHC	DFS	Tertile	All	0.343	0.580	<.001	84	view →
THCA	OS	Tertile	II,III,IV	0.171	0.824	<.001	69	view →
PAAD	DFS	Tertile	All	0.808	0.460	.008	51	view →
CESC	OS	Tertile	IV	0.121	0.591	.029	36	view →
LUAD	DFS	Tertile	III,IV	0.876	0.454	.012	30	view →
SKCM	OS	Tertile	II,III,IV	0.146	0.401	.008	15	view →
SARC	OS	Tertile	All	0.642	0.880	.001	15	view →
BRCA	DFS	Tertile	III,IV	1.000	0.865	.031	6	view →
COAD	OS	Tertile	II,III,IV	0.664	0.816	.039	6	view →
LAML	DFS	Tertile	All	0.866	0.547	.048	6	view →
ESCA	OS	Tertile	II,III,IV	0.644	0.420	.032	3	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 13 lineages.

GRM7-AS2–KIRC (DFS)

Open the KIRC breakdown →