GRM7-AS2

Across TCGA pan-cancer cohorts, GRM7-AS2 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of GRM7-AS2’s most consistent transcriptional readouts.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where GRM7-AS2 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types GRM7-AS2 is over-expressed in tumor.

LUSC, COAD, and BRCA are the cancer types where GRM7-AS2 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in GRM7-AS2 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUSC	All	All	+0.052	<.001	5	view →
COAD	Male	II,III,IV	+0.121	.011	4	view →
BRCA	Female	All	+0.093	.010	4	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

GRM7-AS2–LUSC

Open the LUSC breakdown →