GRM5

Across TCGA patient cohorts, GRM5 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,546 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GRM5-associated proteins across cancer lineages are RAI14, SPARC, and NFATC4. Each is linked with GRM5 in more than 3 cancer types. Because this analysis shows association rather than direction, both GRM5-to-partner and partner-to-GRM5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GRM5 versus RAI14 in HNSC, with a Pearson correlation of 0.37.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GRM5→partner) and Y-score (partner→GRM5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	RAI14 →	+0.306	+0.287	<.001	.001	3	4
HNSC	SPARC →	+0.615	+0.301	<.001	.001	3	4
BRCA	NFATC4 →	+0.304	+0.020	.003	.007	3	4
CCRCC	PEAK1 →	+0.293	+0.504	<.001	<.001	3	4
PDAC	RASGRF2 →	+0.746	+0.294	<.001	<.001	3	4
GBM	RPL4 →	-0.487	-1.283	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,546 associations by consensus.

GRM5 vs RAI14 — HNSC

Explore this scatter interactively →