GRM1

Across TCGA cell cohorts, GRM1 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,232 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GRM1-associated GO terms across cancer lineages are Negative regulation of myoblast fusion, Positive regulation of viral process, and Regulation of myoblast fusion. Each is linked with GRM1 in more than 9 cancer types. Because this analysis shows association rather than direction, both GRM1-to-partner and partner-to-GRM1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of myoblast fusion grouped by GRM1-low versus GRM1-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GRM1→partner) and Y-score (partner→GRM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Negative regulation of myoblast fusion →	+0.166	+0.106	<.001	.008	3	10
LARGE_INTESTINE	Positive regulation of viral process →	+0.057	+0.022	.004	.005	2	10
STOMACH	Regulation of myoblast fusion →	+0.142	+0.107	<.001	.008	3	9
UPPER_AERODIGESTIVE_TRACT	Establishment of protein localization to organelle →	+0.056	+0.062	<.001	.008	3	9
STOMACH	Regulation of macroautophagy →	+0.067	+0.105	.002	.009	3	9
UPPER_AERODIGESTIVE_TRACT	Transcription initiation at RNA polymerase II promoter →	+0.048	+0.044	.001	.006	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,232 associations by consensus.

Negative regulation of myoblast fusion by GRM1 expression — STOMACH

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