GRK7

Across TCGA patient cohorts, GRK7 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,094 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GRK7-associated proteins across cancer lineages are NACC1, ZZEF1, and CWC22. Each is linked with GRK7 in more than 2 cancer types. Because this analysis shows association rather than direction, both GRK7-to-partner and partner-to-GRK7 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GRK7 versus NACC1 in LSCC, with a Pearson correlation of 0.31.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GRK7→partner) and Y-score (partner→GRK7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	NACC1 →	+0.258	+0.300	<.001	.001	3	3
LSCC	ZZEF1 →	-0.145	-0.220	<.001	<.001	3	3
LSCC	CWC22 →	+0.295	+0.230	<.001	.009	3	3
OV	VPS13C_S737 →	-0.718	-0.092	.005	.004	3	3
LSCC	TOPBP1 →	+0.366	+0.252	<.001	<.001	3	3
HNSC	ARHGEF26_S222 →	+1.058	+0.380	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,094 associations by consensus.

GRK7 vs NACC1 — LSCC

Explore this scatter interactively →