GRK6

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, GRK6 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,235 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible GRK6-associated proteins across cancer lineages are LMNB1, NPM1, and KDM3B. Each is linked with GRK6 in more than 5 cancer types. Because this analysis shows association rather than direction, both GRK6-to-partner and partner-to-GRK6 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GRK6→partner) and Y-score (partner→GRK6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BRCALMNB1 →+0.271+0.639<.001.00136
OVNPM1 →+0.343+0.415<.001.00136
LSCCKDM3B →+0.226+0.390<.001<.00135
OVHNRNPAB →+0.461+0.507<.001<.00135
OVUIMC1 →+0.407+0.721<.001<.00135
OVUIMC1_S653 →+0.505+0.481.004.00635
Each partner links to its Q-omics profile. Showing the 6 strongest of 9,235 associations by consensus.

Exploration