Across TCGA patient cohorts, GRK5 RNA expression is significantly associated with the RNA expression of many other genes, with 19,094 significant associations in total. UVM shows the largest number of these associations.

The most reproducible GRK5-associated genes across cancer lineages are PDGFRB, DCHS1, and ADGRA2. Each is linked with GRK5 in more than 32 cancer types. Because this analysis shows association rather than direction, both GRK5-to-partner and partner-to-GRK5 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GRK5→partner) and Y-score (partner→GRK5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ACC	PDGFRB →	+2.118	+1.669	<.001	<.001	3	33
KIRC	DCHS1 →	+1.541	+1.167	<.001	<.001	3	33
ACC	ADGRA2 →	+1.972	+1.577	<.001	<.001	3	33
DLBC	PAG1 →	+1.488	+0.808	<.001	<.001	3	33
KIRC	FLT4 →	+1.563	+1.150	<.001	<.001	3	32
THYM	ARHGEF6 →	+1.401	+0.924	<.001	<.001	3	32

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,094 associations by consensus.

Exploration

GRK5 survival (RNA) · tumor vs normal (RNA) · all GRK5 data types