GRK5

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, GRK5 mutation is significantly associated with the RNA expression of many other genes, with 1,910 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GRK5-associated genes across cancer lineages are OR10G6, RNU6-1005P, and RNA5SP80. Each is linked with GRK5 in more than 1 cancer types. Because this analysis shows association rather than direction, both GRK5-to-partner and partner-to-GRK5 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GRK5→partner) and Y-score (partner→GRK5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
COADOR10G6 →+0.144+3.670<.001.00232
COADRNU6-1005P →+0.594+2.460.002.00932
COADRNA5SP80 →+0.157+4.142<.001.00632
COADRPS2P39 →+0.286+2.463<.001.00932
COADRN7SL288P →+0.336+3.772<.001<.00132
COADMIR4669 →+0.682+3.135<.001.00832
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,910 associations by consensus.

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