Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts
Across TCGA patient cohorts, GRK5 mutation is significantly associated with the total protein of many other genes, with 50 significant associations in total. UCEC shows the largest number of these associations.
The most reproducible GRK5-associated genes across cancer lineages are Shc_pY317, MEK1, and Bax. Each is linked with GRK5 in more than 2 cancer types. Because this analysis shows association rather than direction, both GRK5-to-partner and partner-to-GRK5 results are reported.
Each partner links to its own Q-omics profile.
mutation associated genes by consensus
Ranked by combined sampling and lineage consensus. X-score (GRK5→partner) and Y-score (partner→GRK5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.