Across TCGA cell cohorts, GRK5 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,046 significant associations in total. BONE shows the largest number of these associations.

The most reproducible GRK5-associated GO terms across cancer lineages are Mitotic centrosome separation, Tachykinin receptor signaling pathway, and Nuclear export. Each is linked with GRK5 in more than 7 cancer types. Because this analysis shows association rather than direction, both GRK5-to-partner and partner-to-GRK5 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GRK5→partner) and Y-score (partner→GRK5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Mitotic centrosome separation →	+0.174	+1.218	<.001	<.001	3	8
BONE	Tachykinin receptor signaling pathway →	+0.284	+1.485	<.001	<.001	3	8
BREAST	Nuclear export →	+0.046	+0.719	.002	.005	3	8
PANCREAS	ATP metabolic process →	+0.057	+1.245	.006	.006	3	7
PANCREAS	Phosphatidylinositol metabolic process →	+0.060	+1.808	<.001	<.001	3	7
SOFT_TISSUE	Epithelial cell differentiation involved in prostate gland development →	+0.157	+1.226	.001	.003	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,046 associations by consensus.

Exploration

GRK5 survival (RNA) · tumor vs normal (RNA) · all GRK5 data types