Across TCGA cell cohorts, GRIN3A mutation is significantly associated with the RNA expression of many other genes, with 1,092 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible GRIN3A-associated genes across cancer lineages are IPO11, CHCHD1, and MINPP1. Each is linked with GRIN3A in more than 2 cancer types. Because this analysis shows association rather than direction, both GRIN3A-to-partner and partner-to-GRIN3A results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GRIN3A→partner) and Y-score (partner→GRIN3A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	IPO11 →	+0.467	+3.252	.002	.002	3	3
SKIN	CHCHD1 →	+0.507	+3.451	.002	.002	3	2
LARGE_INTESTINE	MINPP1 →	+0.684	+2.714	<.001	.002	3	2
LARGE_INTESTINE	SUFU →	+0.472	+2.628	.006	.002	3	2
LARGE_INTESTINE	MRPS27 →	+0.592	+2.459	.002	.006	2	3
LUNG_NSCLC_LUAD	NISCH →	+0.522	+3.495	.004	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,092 associations by consensus.

Exploration

GRIN3A survival (RNA) · tumor vs normal (RNA) · all GRIN3A data types