GRIN2D

Across TCGA cell cohorts, GRIN2D RNA expression is significantly associated with the go_rna of many other GO terms, with 4,148 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GRIN2D-associated GO terms across cancer lineages are Regulation of cholesterol efflux, Transition metal ion transport, and Homologous chromosome segregation. Each is linked with GRIN2D in more than 7 cancer types. Because this analysis shows association rather than direction, both GRIN2D-to-partner and partner-to-GRIN2D results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of cholesterol efflux grouped by GRIN2D-low versus GRIN2D-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GRIN2D→partner) and Y-score (partner→GRIN2D) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Regulation of cholesterol efflux →	+0.123	+1.289	.001	<.001	3	8
BLOOD_Leukemia	Transition metal ion transport →	+0.063	+1.138	<.001	<.001	3	7
LUNG_NSCLC_LUSC	Homologous chromosome segregation →	-0.161	-2.158	<.001	.001	3	7
BLOOD_Leukemia	Triglyceride-rich lipoprotein particle clearance →	+1.204	+1.209	<.001	<.001	3	7
BLOOD_Leukemia	Positive regulation of sterol transport →	+0.090	+0.928	<.001	<.001	3	7
BLOOD_Leukemia	Positive regulation of cholesterol transport →	+0.090	+0.928	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,148 associations by consensus.

Regulation of cholesterol efflux by GRIN2D expression — BONE

Explore this box plot interactively →