Across TCGA patient cohorts, GRIN2A protein abundance is significantly associated with the RNA expression of many other genes, with 2,101 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GRIN2A-associated genes across cancer lineages are PRODH, SOX10, and SEPTIN3. Each is linked with GRIN2A in more than 1 cancer types. Because this analysis shows association rather than direction, both GRIN2A-to-partner and partner-to-GRIN2A results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GRIN2A→partner) and Y-score (partner→GRIN2A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PRODH →	+0.702	+0.385	<.001	<.001	3	1
GBM	SOX10 →	+0.933	+0.342	.006	<.001	3	1
GBM	SEPTIN3 →	+1.313	+0.396	<.001	.001	3	1
GBM	SUN2 →	+0.498	+0.381	<.001	.001	3	1
GBM	RASL10A →	+0.890	+0.423	<.001	<.001	3	1
GBM	NEFH →	+1.141	+0.405	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,101 associations by consensus.

Exploration

GRIN2A survival (RNA) · tumor vs normal (RNA) · all GRIN2A data types