Across TCGA cell cohorts, GRIN2A RNA expression is significantly associated with the go_rna of many other GO terms, with 843 significant associations in total. CNS shows the largest number of these associations.

The most reproducible GRIN2A-associated GO terms across cancer lineages are Excitatory postsynaptic potential, Regulation of postsynaptic membrane potential, and Negative regulation of complement-dependent cytotoxicity. Each is linked with GRIN2A in more than 6 cancer types. Because this analysis shows association rather than direction, both GRIN2A-to-partner and partner-to-GRIN2A results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GRIN2A→partner) and Y-score (partner→GRIN2A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Excitatory postsynaptic potential →	-0.057	-0.396	.003	.006	3	7
OVARY	Regulation of postsynaptic membrane potential →	-0.109	-0.906	<.001	.003	3	6
LUNG_NSCLC_LUSC	Negative regulation of complement-dependent cytotoxicity →	+0.278	+0.191	.002	<.001	3	6
LUNG_NSCLC_LUSC	Protein targeting to vacuole involved in autophagy →	+0.204	+0.190	.003	.005	3	6
OVARY	Membrane depolarization during action potential →	-0.077	-0.454	.002	.009	3	6
LUNG_NSCLC_LUSC	Maintenance of protein localization in organelle →	+0.120	+0.214	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 843 associations by consensus.

Exploration

GRIN2A survival (RNA) · tumor vs normal (RNA) · all GRIN2A data types