GRIK5

Across TCGA patient cohorts, GRIK5 mutation is significantly associated with the RNA expression of many other genes, with 4,848 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GRIK5-associated genes across cancer lineages are SNX24, RN7SL248P, and COL9A1. Each is linked with GRIK5 in more than 3 cancer types. Because this analysis shows association rather than direction, both GRIK5-to-partner and partner-to-GRIK5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SNX24 grouped by GRIK5-low versus GRIK5-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GRIK5→partner) and Y-score (partner→GRIK5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SNX24 →	+0.335	+2.137	.002	<.001	3	4
UCEC	RN7SL248P →	+0.039	+2.513	<.001	.004	3	3
COAD	COL9A1 →	-0.801	-2.893	.001	.001	3	3
COAD	F10 →	-0.923	-2.906	.008	.001	3	3
LUAD	MIR6775 →	+0.579	+2.696	.001	.002	3	3
UCEC	JOSD1 →	+0.372	+1.830	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,848 associations by consensus.

SNX24 by GRIK5 expression — UCEC

Explore this box plot interactively →